In immutable server instances, state-isolation is done by having state be elsewhere (like in a centralized logger and a database)
When it comes to writing code, the number one most important skill is how to keep a tangle of features from collapsing under the weight of its own complexity. I've worked on large telecommunications systems, console games, blogging software, a bunch of personal tools, and very rarely is there some tricky data structure or algorithm that casts a looming shadow over everything else. But there's always lots of state to keep track of, rearranging of values, handling special cases, and carefully working out how all the pieces of a system interact. To a great extent the act of coding is one of organization. Refactoring. Simplifying. Figuring out how to remove extraneous manipulations here and there.